产品货号：
Z27647
中文名称：
TAB3抗体
英文名称：
Anti-TAB3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TAB3 Antibody |
| 指标别名 | TAB3;MAP3K7IP3;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;NF-kappa-B-activating protein 1;TAK1-binding protein 3;TAB-3;TGF-beta-activated kinase 1-binding protein 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC |
| 基因名称 | TAB3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TAB3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TAB3.The immunogen is located within amino acids 40 - 90 of TAB3. |
| 计算分子量 | 79kDa |
| 成分 | TAB3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TAB3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TAB3 functions in the NF-kappaB signal transduction pathway.It and the similar and functionally redundant protein TAB2,form a ternary complex with the protein kinase TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1.Subsequent TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor.Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1;upon induction of autophagy,these proteins dissociate from Beclin-1 and bind TAK1.Overexpression of TAB2 and TAB3 inhibit autophagy,while their depletion triggers it,suggesting that TAB2 and TAB3 act as a control point for autophagy. |
| Uniprot ID | Q8N5C8 |
| 基因名全称 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 |
| 蛋白名全称 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 |
| 推荐稀释比 | TAB3 antibody can be used for detection of TAB3 by immunohistochemistry at 5μg/mL.Antibody validated:Immunohistochemistry in human samples.All other applications and species not yet tested. |
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